In a study done on young adult mice, a compound responsible for increased secretion of IGF-1 in muscle fibers was administered. There was an average increase of 15% in muscle mass and a 14% increase in strength. When the study was then conducted on adult mice, there was a 27% increase in strength in the injected muscles as compared with non-injected muscles. It was also found to prevent aging of the muscles. Muscle mass and muscle fiber growth were similar to the levels found in young adults. These effects are most likely due to the ability of IGF-1 to activate satellite cells, therefore stimulating muscle rejuvenation (1).
Tren is an extremely androgenic hormone, and as a result well known for promoting androgenic side effects. Hair loss and acne in men who are predisposed are both possible. Body hair growth is also possible. If you are not genetically predisposed no amount of Tren on earth with cause these issues. The androgenic side effects of Tren are truly based on genetic response. When it comes to hair loss, if you are predisposed to male pattern baldness, meaning at some point you’re going to lose your hair regardless of steroid use , Tren is one of the fastest ways to ensure you lose your hair a little sooner.
Virilization is a serious androgenic side effect of Tren. It is very difficult for a woman to use Tren without some level of virilization and makes it a steroid that’s almost never recommended for female use.
Important Note: The 5-alpha reductase enzyme does not metabolize the Trenbolone hormone. This means 5-alpha reductase inhibitors like Finasteride will not affect the androgenicity of the hormone.
The Stanozolol hormone can be one of the few anabolic androgenic steroids women can use safely; while it is not the absolute mildest in nature for a woman it is up high on the list. Issues regarding the steroids hepatic nature as well as its effects on lipid profiles remain the same with women but the female athlete must also necessarily be aware of virilization. For the female athlete, the Winstrol side effects revolving around virilization will be the most concerning as such effects can destroy a womans femininity. Common virilization effects include a deepening of the vocal chords, body-hair growth and enlargement of the clitoris. The majority of women who supplement with the Stanozolol hormone, if they keep the dose low and use for very short periods will be fine. If you are a female Winstrol user and you begin to notice virilization symptoms simply discontinue use and you will be fine; nothing will change. It is when the symptoms are ignored, use is continued and the symptoms are allowed to set in that many women develop a problem; remember, man or woman responsible use is always your best friend.